Download A History of Immunology (2nd Edition) by Arthur M. Silverstein PDF

By Arthur M. Silverstein

Written by way of an immunologist, this ebook strains the idea that of immunity from precedent days as much as the current day, analyzing how altering recommendations and applied sciences have affected the process the technological know-how. It indicates how the personalities of scientists or even political and social components prompted either thought and perform within the box. With interesting tales of medical disputes and transferring medical developments, each one bankruptcy examines an enormous part of this self-discipline that has been so crucial to the advance of contemporary biomedicine. With its biographical dictionary of significant scientists and its lists of important discoveries and books, this quantity will give you the so much entire historic reference within the box.

. Written in a chic kind through long-time training immunologist
. Discusses the altering theories and applied sciences that guided the field
. Tells of the interesting disputes between in demand scientists
. Lists all of the vital discoveries and books within the field
. Explains intimately the various Nobel prize-winning contributions of immunologists

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Extra resources for A History of Immunology (2nd Edition)

Sample text

Its focus was on the question of whether innate and acquired immunity to infection could be best explained by cellular or by humoral mechanisms. In that exciting decade when remarkable discoveries crowded close on one another’s heels, when new mechanisms, new organisms, new diseases appeared with almost every issue of the journals, the protagonists from one or the other camp grasped each new item eagerly to bolster their own theory, or to cast doubt upon that of the opposition. The lines that divided the two camps were fairly sharply drawn.

Fuller’s argument speaks elegantly for itself, and would appear to explain all of the known phenomenology of smallpox. Contagion and a specific etiologic agent are represented by the male element that comes from without, and specifically fertilizes the female elements (the ovula) that reside innately within each of us. As with all seeds, once germinated and sprouted the body suffers a depletion of the specific seeds of that disease, so that thenceforth new etiologic agents will fall upon sterile soil.

A similar view was repeated in 1764 by the remarkable Italian physician Angelo Gatti,43 who for a time joined the philosophes in Paris to become one of the chief proponents of inoculation in France. In a book notably in advance of its times for its view of infection, resistance, and disease, and in its attempt to cut through the often meaningless jargon of contemporary medicine, Gatti compared smallpox infection and acquired immunity to a body which a single spark can set afire, but which has thenceforth become ‘‘incombustible’’ although surrounded by flames.

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