Download Actin-Monomer-Binding Proteins by Pekka Lappalainen PDF

By Pekka Lappalainen

The actin cytoskeleton performs a imperative position in lots of mobile methods together with phone motility, cytokinesis, endocytosis and phagocytosis. The constitution and dynamics of the actin cytoskeleton is regulated via a good number of proteins that engage with monomeric and/or filamentous actin. Actin monomer binding proteins offers a accomplished view on actin monomer-binding proteins and the mechanisms through which they give a contribution to actin dynamics and numerous actin-dependent mobile tactics. This new name includes chapters that describe the fundamental mechanisms of actin dynamics in addition to the structural ideas through which a variety of actin-binding proteins have interaction with actin.

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Putting a new twist on actin: ADF/cofilins modulate actin dynamics. Trends Cell Biol 1999; 9(9):364-370. 31. Chen H , Bernstein BW, Bamburg JR. Regulating actin-filament dynamics in vivo. Trends Biochem Sci 2000; 25(l):19-23. 32. Zebda N , Bernard O, Bailly M et al. Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and s u b s e q u e n t lamellipod extension. J Cell Biol 2 0 0 0 ; 151(5):1119-1128. 33. Ghosh M, Song X, Mouneimne G et al. Cofilin promotes actin polymerization and defines the direction of cell motiHty.

Genes Cells 2003; 8(10):811-824. 80. Nagata-Ohashi K, O h t a Y, G o t o K et al. A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia. J Cell Biol 2004; 165(4):465-471. 81. Gohla A, Birkenfeld J, Bokoch C M . Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics. Nat Cell Biol 2005; 7(l):21-29. 82. Soosairajah J, Maiti S, Wiggan O et al. Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.

Trends Cell Biol 2004; l4(8):461-469. 117. Loisel T P , Boujemaa R, Pantaloni D et al. Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature 1999; 401 (6753):613-316. 118. Carlier MF, Wiesner S, Le Clainche C et al. Actin-based motility as a self-organized system: Mechanism and reconstitution in vitro. C R Biol 2003; 326(2):161-170. ADF/Cofilin Proteins 27 119. Laurent V, Loisel T P , Harbeck B et al. Role of proteins of the EnaA^ASP family in actin-based motility of Listeria monocytogenes.

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